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Diapharma/Technozym® ADAMTS-13 Fluorogenic Activity/Antigen/5450551/Kit/48 tests

  • 产品编号: 5450551
  • 美  元  价: $0.00
  • 会  员  价: 待定
  • 品       牌: Diapharma
  • 产       地: 美国
  • 公       司: Diapharma Group, Inc.
  • 产品分类: ref="." class="index">首页 > Diapharma/Technozym® ADAMTS-13 Fluorogenic Activity/Antigen/5450551/Kit/48 tests
  • 公司分类: Coagulation Kits
:Kit/48 tests
Diapharma/Technozym® ADAMTS-13 Fluorogenic Activity/Antigen/5450551/Kit/48 tests
  • Diapharma/Technozym® ADAMTS-13 Fluorogenic Activity/Antigen/5450551/Kit/48 tests
商品介绍

Description:

Technozym® ADAMTS-13 ELISA is a Fluorogenic ELISA kit for the determination of ADAMTS-13 activity and antigen concentration in human plasma. ADAMTS-13 is the enzyme that cleaves vWF under laminar flow conditions. A functional defect of this enzyme leads to the presence of higher molecular weight forms of vWF and thus to increased platelet aggregation, mainly in the microvasculature.

Kit Composition:

  • ELISA test strips (1×6 for 48T), with 8 wells each, coated with a monoclonal anti ADAMTS13, directed against the CUB domain; the drying agent is supplied in an aluminium bag.
  • Washing buffer concentrate (PBS; pH 7.3); containing detergent; 0.01% merthiolate; 1 vial, 100 mL.
  • Incubation buffer (PBS; pH 7.3); contains stABIliser protein; 0.01% merthiolate; and dye, 1 vial, 100 mL, ready for use.
  • Calibrators (standards) numbered from 1 to 5; lyophilised; 1 vial each; 0.5 mL. Concentrations are lot-specific; consult the label on the vial or the included batch table.
  • High and low control plasma; lyophilised; 1 vial each; 0.5mL. Concentrations are lot-specific; consult the label on the vial.
  • Activity substrate; 1 vial for 48T; 3 mL each, lyophilised.
  • Conjugate: anti-ADAMTS-13 POX; dyed blue; 1 vial, 0.3 mL.
  • Antigen substrate: 1 vial, 6 mL.
  • Stable peroxide solution; 1 vial, 0.7mL.
  • Stop solution for antigen substrate: 1 vial; 6 mL; ready to use.
  • Adhesive film: for ELISA test strips; 2 pieces.

Advantages:

  • Allows determination of ADAMTS-13 activity below 5%
  • Ready-to-use coated ELISA plate
  • Easy to use in-house assay can lead to significant cost savings
  • Plate-based assay with commonly used fluorescent ADAMTS-13 activity substrate
  • Less interferences compared to solution-based fluorescent assays
  • Calibrators and controls included
  • Sample used undiluted
  • Both activity and antigen levels in one assay
  • Excel evaluation software available

Assay Principle:

adamts13 fluorescent

Background:

ADAMTS-13

ADAMTS-13 (a disintegrin-like and metalloproteinase with thrombospondin type 1 motif 13) is an enzyme (vWF-cleaving protease or vWF-CP) that specifically cleaves von Willebrand Factor (vWF) multimers.

品牌介绍

Mission Statement

Diapharma Group, Inc. in West Chester, Ohio sells hemostasis, thrombosis, platelet function testing, instrumentation, and apoptosis products in the diagnostic and research fields and provides strong technical competence and experience to ensure customer expectations will be met or exceeded.

diapharma hemostasis chromogenic clotting elisa assay test kit

 

History

The Diapharma Group, Inc. formed on January 1, 1997 from Pharmacia Hepar, Inc. in Franklin, Ohio, and began as the exclusive US and Canadian distributor of the Chromogenix substrates and assays.

Over a quarter-century ago, Chromogenix developed the first chromogenic substrate technology under the former name, Kabi Diagnostica. Kabi later merged with Pharmacia. Some of Diapharma’s current staff worked inside the Chromogenix department within Pharmacia’s heparin manufacturing plant.

In 1998, Diapharma moved to West Chester, Ohio, where it remains today. Over the years, Diapharma expanded its product line to include a variety of hemostasis, cell death, platelet function, ecotoxicology, assays, reagents, antibodies and instruments from superior manufacturers.

In 2017, Diapharma celebrated twenty years of success


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