请使用支持JavaScript的浏览器! Diapharma-Platelet Function Testing-Diapharma/Multiplate® RISTOtest/MP0140/Kit/1ml + 5 micro test tubes
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Diapharma/Multiplate® RISTOtest/MP0140/Kit/1ml + 5 micro test tubes

  • 产品编号: MP0140
  • 美  元  价: $0.00
  • 会  员  价: 待定
  • 品       牌: Diapharma
  • 产       地: 美国
  • 公       司: Diapharma Group, Inc.
  • 产品分类: ref="." class="index">首页 > Diapharma/Multiplate® RISTOtest/MP0140/Kit/1ml + 5 micro test tubes
  • 公司分类: Platelet Function Testing
:Kit/1ml + 5 micro test tubes
Diapharma/Multiplate® RISTOtest/MP0140/Kit/1ml + 5 micro test tubes
  • Diapharma/Multiplate® RISTOtest/MP0140/Kit/1ml + 5 micro test tubes
商品介绍

Description:

DISCONTINUED – REPLACEMENT: MP0240

Multiplate® RISTOtest is a research reagent kit for the quantitative in vitro determination of von Willebrand Factor (vWF)- and glycoprotein Ib (GpIb)-dependent platelet aggregation studies on the Multiplate® analyzer.

Ristocetin is an antimicrobial substance which forms complexes with vWF (von Willebrand factor). In this complex, vWF changes its conformation in a way that allows it to bind to platelets. The binding of ristocetin-vWF complexes leads to the aggregation and activation of platelets. This activation relies on the binding of vWF to the GPIb receptor and it is inhibited by the action of Aspirin®. This explains the Aspirin® sensitivity of RISTOtest. Complete lack of aggregation in the research RISTOhigh test can be caused by an absence of GPIb receptors on the platelet surface (Bernard-Soulier syndrome) or by an absence of vWF in the solution (vWD type III).

Kit Composition:

Reagents, Storage and StABIlity

  • MP0140: Multiplate® RISTOtest Reagent, Kit, Ristocetin, 1 x 1.0 mL, lyophilized (10 mg/ml), with 5 micro test tubes for aliquotation. Unopened vials of the RISTOtest reagent must be stored at 2-8°C. The reagent is stable until the expiry date printed on the vial label when stored under these conditions. If reconstituted reagent is not aliquoted into micro test tubes, the original vial should be stored in an upright position. Stable 7 days after reconstitution when stored at 2-8°C, 4 weeks at < -20°C or 24 hours at room temperature after one time thawing.

Also Available

  • MP0094: Multiplate® RISTOtest Aliquot Vials, Bag, 100 micro tubes color coded (blue) for for aliquotation.
  • MP0194: Multiplate® RISTOtest Reagent, Bag, Ristocetin, 1 x 1.0 mL, lyophilized (10 mg/ml), without micro test tubes for aliquotation.
  • MP0240: Multiplate® RISTOtest Reagent, Kit, Ristocetin, 3 x 1.0 mL, lyophilized (10 mg/mL), without micro test tubes for aliquotation.

Measurement Principle:

RISTOtest reagent contains ristocetin. Ristocetin forms a complex with vWF from the sample. This complex binds to the platelet GpIb receptor and triggers platelet activation and aggregation. RISTOtest can be applied in two concentrations: In RISTOhigh test a high concentration of ristocetin (0.77 mg/mL) is applied, which normally induces a strong platelet aggregation. Abolished aggregation in RISTOhigh test can be based on a deficiency of GpIb receptors or vWF. In RISTOlow test a lower concentration of ristocetin (0.2 mg/mL) is applied which normally does not induce a strong aggregation response. A higher than expected aggregation in RISTOlow test may indicate an enhanced aggregation tendency of vWF (vWD type IIb).

品牌介绍

Mission Statement

Diapharma Group, Inc. in West Chester, Ohio sells hemostasis, thrombosis, platelet function testing, instrumentation, and apoptosis products in the diagnostic and research fields and provides strong technical competence and experience to ensure customer expectations will be met or exceeded.

diapharma hemostasis chromogenic clotting elisa assay test kit

 

History

The Diapharma Group, Inc. formed on January 1, 1997 from Pharmacia Hepar, Inc. in Franklin, Ohio, and began as the exclusive US and Canadian distributor of the Chromogenix substrates and assays.

Over a quarter-century ago, Chromogenix developed the first chromogenic substrate technology under the former name, Kabi Diagnostica. Kabi later merged with Pharmacia. Some of Diapharma’s current staff worked inside the Chromogenix department within Pharmacia’s heparin manufacturing plant.

In 1998, Diapharma moved to West Chester, Ohio, where it remains today. Over the years, Diapharma expanded its product line to include a variety of hemostasis, cell death, platelet function, ecotoxicology, assays, reagents, antibodies and instruments from superior manufacturers.

In 2017, Diapharma celebrated twenty years of success


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